Conor Dorgan
Ms. Graf/Mr. Sauer
American Studies
March 25, 2009
Penicillin and the Birth of Modern Medicine
Although Ian Fleming is commonly acknowledged as discovering penicillin, a mold that attacks many bacterial forms without harming other cells, it is not so often recognized that his accidental discovery may never have brought about the drug as we know it without Ernst Chain’s discovery in 1938 of a paper Fleming had written ( Bowler 452). Chain’s work developing the antibiotic with Howard Florey would launch penicillin, and medicine in general, into unimagined territory (Bowler 452). As satirized in a cartoon on cartoonstock.com ( The cartoon reads: penicillin is called the ‘wonder drug’ because any time the doctor wonders what you have got, that’s what you get), the drug has enjoyed widespread use and popularity, but these are only small aspects of its influence. As the harbinger of today’s antibiotics, penicillin has defined modern medical practice, birthed a multi-billion dollar pharmaceutical industry, and fundamentally changed the American lifestyle.
Today’s general practitioners have Penicillin to thank for their role in the medical community. Born in Greece in 460. A.D., Hippocrates, commonly attributed as being the father of medicine, was the founder and representative of a medicinal school of thought that valued an approach based on observation and logic, rather than the mythological superstitions that were popular at the time (Delvey). In short, Hippocrates was one of the world’s first physicians and his philosophy was not unlike the wellness and lifestyle trend of today. “[Hippocrates] believed in the natural healing process of rest, a good diet, fresh air and cleanliness” according to Josephine Delvey of San Jose State University, and this personable, wellness-based style of diagnosis continued until the 20th century, when, with the popularization of Penicillin, the role of the physician fundamentally changed. In Robert Bud’s Penicillin: Triumph and Tragedy, Bud illustrates how one drug legitimized an industry and shifted the role of the doctor to encompass, and be dominated by, pharmaceutical prescription. During WWII, penicillin helped to save “countless lives” (Steinert) and its wartime success and global use treating a variety of formerly lethal bacteria created “ [a brand that] seemed the very model of the means by which post-war aspirations of a break from the suffering of pre-war days could be achieved” (Bud 214) and the effect, according to Swedish professor Gunnar Biorck, was “more hospitals, more group practices, less individual medicine” (Bud). With new technology and funding (Bud), now there was an industry. Physicians were no longer the freelance, personable professionals of Hippocrates’ time onward, but were agents to satisfy the public’s craze for antibiotics and effectively all pharmaceuticals due to what Bud describes as penicillin’s assimilation into patients’ trust and “life worlds”. By the end of the century, this “cultural branding” would create a multi-billion dollar industry (Gatyas and Savage).
“The pharmaceuticals market is one of the most profitable sectors in the global economy” according to Adriana Petryna, Andrew Lakoff, and Arthur Kleinman in Global Pharmaceuticals. The industry is expected to exceed $820 billion in sales in 2009 according to IMS Health (Gatyas and Savage) and despite economic slowdown is “reflecting sustained double-digit growth in key emerging countries.” Antibiotics are responsible for the growth of the entire industry, but in the case of developing countries, antibiotics maintain significant application as well. “ [The] need for antibiotics is driven by the high incidence of infectious disease” (Okeke, Lamikanra, and Edelman), to the extent that “antibiotic resistance” has become an issue. Health care spending in developed countries, however, remains strong. In the U.S., government spending under the broader healthcare industry exceeds $1 trillion (Chantrill). Whether they like it or not, officials are forced to comply with the force described by Robert Budd as the “pressure of modern expectations” placed on them by the public. At what point does spending based on the public’s affection for early antibiotics become superfluous health care consumerism? This pharmaceutical fervor married with consumerist tendencies was to change American lifestyle.
The rise of pharmaceuticals has created new American attitudes and a new lifestyle in the 21st century. In his book High Level Wellness: An Alternative to Doctors, Drugs, and Disease, Donald Ardell, P.h.d., argues “Modern medicine is a wonderful thing but there are two problems: People expect too much of it, and too little of themselves.” Antibiotics have reduced the occurrence of former killers such as Pneumonia, but in the process of trivializing treatment, are Americans trivializing their own health? Have we lost the wellness values Hippocrates swore by in his foundation of modern medicine? “Increasingly, [Americans] treat [health care] like everything else” claims David Gratzer, in an editorial in the San Francisco Examiner, “They expect to get what they want, when they want it”. This redefinition of health as a product that can be bought is taking its toll on Americans’ habits. Childhood obesity rose from 5% of the American population to 17% between 1980-2004 (Levi, Juliano, and Segal 3) and the number of Americans who suffer sleep deprivation “moderately to severely” is 40% (Statistics:). Both of these conditions have the potential to cause disease according to the Mayo Clinic. Treatments of disease have been idolized while prevention has been ignored. It may seem a stretch that penicillin is causing Americans disease, but by creating the pharmaceutical industry, penicillin created the means by which a consumerist society could devalue their own health to dangerously low levels.
Neither Fleming, who discovered penicillin, nor Merck, the company who first sold it commercially (Bowler 454) could have foreseen the influence the drug would have on America and the world. Penicillin would change the role of the physician from a personal, wellness mentor to a clinical diagnostic tool and prescriptive agent. Within half a century it was responsible for a multi-billion dollar industry driven by both public and government demand, as well as bringing about a negative consumerist image of health and wellness.
Works Cited
Bowler, Peter J., and Iwan Rhys Morus. Making Modern Science A Historical Survey. New York: University Of Chicago P, 2005.
Bud, Robert. Penicillin Triumph and Tragedy. New York: Oxford UP, USA, 2007.
Chantrill, Christopher. “US Health Care Spending 1792-2014 – Charts.” Federal Spending, State and Local Public Spending 1792-2014 – Charts. June 2008. 12 Mar. 2009 <http://www.usgovernmentspending.com/us_health_care_spending_10.html#usgs30210>
Gatyas, Gary, and Clive Savage. “News Releases – IMS Health Forecasts 4.5 – 5.5 Perc – IMS Health.” IMS Health-Intellgence. Applied. 29 Oct. 2008. IMS. 12 Mar. 2009 <http://www.imshealth.com/portal/site/imshealth/menuitem.a46c6d4df3db4b3d88f611019418c22a/?vgnextoid=9e553599b554d110VgnVCM100000ed152ca2RCRD&vgnextfmt=default>.
Gratzer, David. “Consumerism: A Prescription for Change.” The Examiner [San Francisco] 2 Feb. 2007: 1-1.
“Heart disease: Causes – MayoClinic.com.” Mayo Clinic medical information and tools for healthy living – MayoClinic.com. 28 Jan. 2009. Mayo Clinic. 12 Mar. 2009 <http://www.mayoclinic.com/health/heart-disease/DS01120/DSECTION=causes>.
Delvey, Josephine. “Hippocrates.” San José State University – Powering Silicon Valley. 12 Mar. 2009 <http://www.sjsu.edu/depts/Museum/hippoc.html>.
Levi, Jeffrey, Chrissie Juliano, and Laura Segal. Trust for America’s Health – Preventing Epidemics. Protecting People. Aug. 2006. 12 Mar. 2009 <http://healthyamericans.org/reports/obesity2006/Obesity2006Report.pdf>.
Petryna, Adriana, Andrew Lakoff, and Arthur Kleinman. Global Pharmeceuticals Ethics, Markets, Practices. New York: Duke UP, 2006.
Okeke, Iruka N., Adebayo Lamikanra, and Robert Edelman. “Socioeconomic and Behavioral Factors Leading to Acquired Bacterial Resistance toAntibiotics in Developing Countries.” Centers for Disease Control and Prevention. Mar. 2009. 12 Mar. 2009 <http://www.cdc.gov/ncidod/EID/vol5no1/okeke.htm>.
Penicillin Joke. Digital image. Cartoon Stock. 12 Mar. 2009 <http://www.cartoonstock.com/lowres/ear0578l.jpg>.
“Statistics: Sleep Deprivation in America.” ISlumber.com — Tools, tips for better sleep, improving sleep habits, interactive sleep log. 2007. 12 Mar. 2009 <http://islumber.com/page.jhtml?id=islumber/articles/stats_sleepDeprivation.inc>.
Steinert, David. “History of WWII Medicine.” World War II- Combat Medic. 05 Apr. 2002. 12 Mar. 2009 <http://home.att.net/~steinert/wwii.htm#The%20Use%20of%20Penicillin%20in%20World%20War%20II>.